Albizzia julibrissin herb and plant Chinese herb
Albizzia julibrissin Durazz (Leguminosae) has been used
in traditional oriental medicine. Cortex Albizziae, the stem bark of the
leguminous plant Albizzia julibrissin, is specified in Chinese pharmacopoeia as
a traditional Chinese medicine used to relieve melancholia and uneasiness of
body and mind, invigorate the circulation of blood and subside a swelling.
There are claims that Albizzia julibrissin herb has the
potential to be useful as an antidepressant.
Albizzia julibrissin herb
substances
The bark of
Albizzia julibrissin herb has triterpenoid saponins
such as julibroside, flavonoids, and hehuanoside A.
Blood vessels
Anti-angiogenic activity of julibroside J8, a natural product isolated
from Albizia julibrissin.
Phytomedicine. 2009; Laboratory of Natural Medicine, School of Medicine
and Pharmaceutics, Jiangnan University, Wuxi, Jiangsu, PR China.
The purpose of this study was to investigate the anti-angiogenic properties
of julibroside J(8), a triterpenoid saponin isolated from Albizia julibrissin.
METHODS: In the presence of juliborside J(8,) the growth of human microvascular
endothelial cells (HMEC-1), four human tumor cell lines, and a normal cell line
(MRC-5) was evaluated by MTT assay. The in vivo anti-angiogenic effect of
julibroside J(8) was evaluated on a chorioallantoic membrane (CAM) and in
transplanted colon carcinoma cells in a nude mice neovascularisation model.
RESULTS: Treatment with 0.5-4 microg/ml julibroside J(8) resulted in
dose-dependent inhibition of growth, migration, and tube formation in HMEC-1
cells; julibroside J(8) also inhibited the formation of microvessels on CAM at a
concentration of 10-50 microg/egg and reduced vessel density within tumor at a
concentration of 0.5-3mg/kg. Julibroside J(8) may be a potent anti-angiogenetic
and cytotoxic drug; further investigation is warranted.
Albizzia julibrissin herb for
depression
Antidepressant-like effects of Albizzia julibrissin in
mice: involvement of the 5-HT1A receptor system.
Pharmacol Biochem Behav. 2007. Department of Pharmacology, College of
Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
The present study was undertaken to investigate the antidepressant-like effects
of the methylene chloride fraction of Albizzia julibrissin using a tail
suspension test in mice. Our findings suggest that methylene chloride fraction
of Albizzia julibrissin exerts its antidepressant-like effect via the 5-HT1A
receptor system.
Albizzia julibrissin herb questions
I don't think you carry this item and I hope you can add it. I bought some albizzia bark from an online seller and ground it to make tea, it was very
relaxing. The stuff was expensive and halfway through I found spiders in the
bark, yuck. I hope you can find a cleaner and cheaper way of providing it.
This is interesting.
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